Jean-François Martini – Virtual

Company: Pfizer

Job title: Executive Director, Translational Oncology Lead, Global Product Development, Oncology

Seminars:

Can Molecular Response Help Predict Clinical Outcome for TKI Treatment in Lung Cancer? 4:35 pm

• Model: Lung cancer, Phase 3 study, with comparator arm, and treatment with tyrosine kinase inhibitors • 3 approaches utilized to examine molecular response either via difference from baseline or via ratio to baseline with arbitrary cut off, and various ways to integrate variant calls from ctDNA • Correlation with clinical outcome (OR and PFS)…Read more

day: Day One